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Symbol Name ID |
Nr3c1
nuclear receptor subfamily 3, group C, member 1 MGI:95824 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Asthma |
| Disease(s) Associated with NR3C1 | |
| asthma |
| Mouse Phenotypes | immune system phenotype |
heart inflammation |
abnormal thymocyte apoptosis |
decreased thymocyte apoptosis |
decreased T cell apoptosis |
cecum inflammation |
thymus hypoplasia |
decreased double-positive T cell number |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased single-positive T cell number |
decreased macrophage cell number |
abnormal monocyte cell number |
abnormal interferon level |
abnormal interleukin level |
abnormal tumor necrosis factor level |
abnormal humoral immune response |
increased interleukin-1 beta secretion |
abnormal interleukin-6 secretion |
increased susceptibility to experimental autoimmune encephalomyelitis |
increased susceptibility to endotoxin shock |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Nr3c1tm1Dage/Nr3c1tm1Dage | |||||||||||||||||||||||
| Nr3c1tm1Ljm/Nr3c1tm1Ljm | |||||||||||||||||||||||
| Nr3c1tm1Dage/Nr3c1+ | |||||||||||||||||||||||
| Nr3c1tm2.1Gsc/Nr3c1+ | |||||||||||||||||||||||
| Nr3c1tm1.1Jaci/Nr3c1tm1.1Jaci Tg(Myh6-cre)2182Mds/0 (conditional) |
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| Nr3c1tm1.1Jda/Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm/0 (conditional) |
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| Nr3c1tm2.1Ljm/Nr3c1tm2.1Ljm Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Nr3c1tm2Gsc/Nr3c1tm2Gsc Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
* | ||||||||||||||||||||||
| Nr3c1tm2Gsc/Nr3c1tm2Gsc Tg(Lck-cre)I57Jxm/0 (conditional) |
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| Nr3c1tm2Ljm/Nr3c1tm2Ljm Tg(Lck-cre)548Jxm/? (conditional) |
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| Nr3c1tm1.1Jda/Nr3c1+ Tg(Lck-cre)548Jxm/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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